Wednesday, October 11, 2017

Translational Health Will Likely Become a TwentyFirst Paradigm for Medicine

Does this sound promising to you?

Essentially metabolic health improves resilience to illness and disease.

Strategic change, paradigm change?. 

Cell heal thyself.  Instead of increasing war on threats to health, increase the non war activities of cell building and regeneration.  This acknowledges that the capacity to be resilient and regenerate is magnitudes stronger than powerful medicine.  Properly understood medicines allow the body to recover and thrive post war. Resilience and recovery is an infinite game rather than a finite game that leads to nursing home care.

"Abstract
Advances in geroscience are allowing scientists and clinicians, for the first time, to consider interventions aimed at directly targeting the hallmarks of aging. Unlike disease-specific approaches, such interventions have the potential to prevent multiple diseases of aging simultaneously, thereby greatly enhancing healthspan for most individuals. Initial clinical data indicates that geroprotective compounds such as rapamycin and metformin may be effective at delaying or reversing age-related disease in otherwise healthy elderly people and companion animals. Here I will provide an overview of the field of translational geroscience, which I believe will become the paradigm for the practice of medicine in the 21st century."

My study of cell science strongly indicates that Nrf2 activators and proteostasis activators via appropriate and signaled pathways that ultimately leads to autophagy or cell quality control, Mitophagy and reduced Endoplasmic Reticulum stress will regenerate and optimize resilience to oxidative stress and age related pleiotropic disorders.

The best example of this is the work of Dale Bredesen MD who in the YouTube video Reversing Alzheimer s has reversed dementia in 1000s of patient.  That is too many magnitudes of Lazarus walking out of their tombs of dementia to be chance alone.
Dr. Bredesen eschews the single drug therapy for root cause correction and developed the right strategy, right tactics and right projects to provide a powerful proof of concept.
I think this approach will impact humanity like Tesla's alternating current. (Analogy intended)
Cell power is the flow of electrons and it's safe production.  Not too hot and not to cool, just right.
Horse power is electron power in all its forms.
http://www.sciencedirect.com/science/article/pii/S2468501117300081

No comments:

Post a Comment