Longevity and Increased Healthspan: A Strategy with Strong Evidence

Interesting article showing that autophagy promotion reduces sarcopenia and improves muscle strength function.  Autophagy inhibition promotes sarcopenia and reduces muscle strength function.

Spermidine, fasting and exercise directly promotes autophagy and without autophagy their actions are blocked.

Sulphoraphane by stimulating ARE antioxidant response element counters oxidative stress and reduces the damaged proteins and DNA that require autophagy and replacement or repair and indirectly aids autophagy.

That is likely the anti-aging effect of these lifestyle and supplements.  The magnitude of all combined should be greater than 30% Healthspan and lifespan as that had been proved with either supplement alone.

http://www.sciencedirect.com/science/article/pii/S1471489216300959